Found 1692 results for "cancer"
The ATR/CHK1 signaling cascade can initiate genome protection responses even when stripped of RPA protein complexes, traditionally considered essential for…
A novel radiopharmaceutical demonstrates efficacy against small-cell lung cancer and neuroendocrine prostate cancer, two notoriously aggressive malignancies…
Clinical trial data reveals that time-limited chronic lymphocytic leukemia treatment produces equivalent survival outcomes compared to indefinite therapy…
French researchers have mapped the mechanisms by which mitochondria migrate between adjacent cells, particularly within tumor environments. This intercellular…
Nondaily and low-intensity smokers in Latin America present distinct cessation challenges that differ markedly from heavy daily users. These lighter smoking…
Marcel Deckert's team at INSERM Nice has identified USP9X as a critical vulnerability in melanoma progression, where this deubiquitinating enzyme stabilizes…
Researchers at INSERM have identified cellular viscosity as a critical biophysical parameter controlling cancer metastasis. Cancer cells with reduced internal…
Nivolumab, a PD-1 checkpoint inhibitor, demonstrates remarkable durability in advanced melanoma patients with survival benefits persisting nearly a decade…
Scientists have engineered circular RNA structures that form self-looping configurations, demonstrating enhanced stability and prolonged therapeutic activity…
Recent trial data indicates that biparametric MRI (bpMRI), which uses only two imaging sequences instead of the standard three or more, demonstrates…
The PRIME trial found that biparametric MRI (bpMRI) performs equivalently to the standard multiparametric MRI (mpMRI) for detecting clinically significant…
The PRIME clinical trial establishes that biparametric MRI (bpMRI) achieves equivalent diagnostic performance to multiparametric MRI (mpMRI) for identifying…
Breast, colorectal, lung, brain, and lymphoid cancers account for approximately 70% of cancer deaths in Americans under 50, with colorectal cancer showing…
Ten patients with severe, treatment-resistant autoimmune conditions—five with antisynthetase syndrome and five with systemic sclerosis—experienced significant…
A population-based screening trial involving over 270,000 Swedish adults demonstrated that both colonoscopy and fecal immunochemical testing (FIT)…
Age-related mutations in blood stem cells, termed clonal hematopoiesis of indeterminate potential (CHIP), appear to amplify the therapeutic benefits of PD-1…
Mammary gland involution following weaning triggers widespread cellular senescence that orchestrates tissue remodeling but simultaneously creates…
A comprehensive WHO analysis examining 30 modifiable risk factors reveals that 40% of global cancer cases stem from preventable causes, representing the most…
Biophysical measurements reveal that metastatic cancer cells undergo measurable changes in internal viscosity that correlate with their ability to detach from…
An international randomized controlled trial demonstrated that structured exercise programs significantly improved both disease-free and overall survival…