Found 1692 results for "cancer"
Cancer incidence is surging across Sub-Saharan Africa, with the region accounting for the majority of new cases in low-income countries globally. This…
Dendritic cells expressing the transcription factor Etv3 demonstrate enhanced capacity to promote immune tolerance rather than inflammatory responses. This…
Cancer immunotherapy drugs targeting the PD-1 checkpoint protein significantly reduced latent HIV reservoirs in co-infected patients, according to…
Blocking the PD-1 immune checkpoint protein triggers interferon-driven antiviral responses that measurably reduce latent HIV reservoirs in cancer patients…
Age-related mutations in blood stem cells, known as clonal hematopoiesis of indeterminate potential (CHIP), appear to improve patient responses to immune…
Researchers compiled 748,679 single cells from multiple acute myeloid leukemia studies to map how age influences gene expression patterns in t(8;21) AML, a…
Marcel Deckert's team at INSERM in Nice has identified USP9X as a critical vulnerability in melanoma's adaptive machinery. This deubiquitinating enzyme…
The FDA has authorized pembrolizumab combined with paclitaxel, optionally with bevacizumab, for treating recurrent ovarian cancers expressing PD-L1 protein…
Analysis of 85,000 older adults in the UK reveals that accumulated daily movement—including light activities like walking or household tasks—provides…
Tumor infiltrating lymphocyte (TIL) therapy combined with checkpoint inhibitors achieved substantial tumor regression across multiple metastatic…
National cancer registry data reveals mortality declined at 2.1% annually for men and 1.4% for women from 2001-2022, maintaining trajectory even through…
National Cancer Institute surveillance data spanning 2010-2019 reveals a striking bifurcation in early-onset malignancies: while 14 cancer types increased in…
NIH investigators identified specific tissue alterations that predict both aggressive breast cancer development in women with benign breast conditions and…
A comprehensive WHO analysis examining 30 modifiable risk factors reveals that 40% of global cancer cases stem from preventable causes, representing the most…
Analysis of 7,619 East Asian genomes identified nearly 29,000 novel methylation quantitative trait loci (mQTLs) that regulate DNA methylation patterns…
Mendelian randomization analysis of 738,000 individuals confirms that elevated BMI causally increases kidney cancer risk by 68% per 5-unit BMI increase, with…
vCATCH technology achieves single-cell resolution mapping of covalent drug binding sites across intact mammalian tissues, offering unprecedented visualization…
Enzalutamide, an androgen receptor inhibitor, demonstrated significant survival benefits in men with biochemically recurrent prostate cancer following initial…
University of South Florida researchers identified elevated omega-6 fatty acid concentrations within colorectal tumor tissue, demonstrating a direct…
Clinical evidence demonstrates that subsidized fruit and vegetable programs yield quantifiable health improvements across diverse populations. Participants…