Breast Cancer Initiating Cells Change With Age, Affecting Treatment Response
Cancer stem cells that initiate breast tumors appear to originate from different mammary cell populations depending on patient age, with older women's tumors…
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Cancer stem cells that initiate breast tumors appear to originate from different mammary cell populations depending on patient age, with older women's tumors…
A novel imaging technique combines TROP2 protein targeting with near-infrared fluorescence to provide real-time visualization of cancer boundaries and lymph…
An off-the-shelf neoantigen vaccine targeting Lynch syndrome has demonstrated both safety and immunogenicity in clinical testing, marking a significant step…
Scientists developed lanthanide nanoparticles that use near-infrared light to selectively reprogram M2-like tumor-associated macrophages in glioblastoma…
Analysis of 171 studies across two decades reveals 59 distinct barriers and facilitators affecting oral nutritional supplement adherence among malnourished…
Focus groups with 31 Black and Hispanic men with localized prostate cancer and their partners identified four key barriers to adopting heart-protective diets…
Researchers identified small nucleolar RNAs (snoRNAs) as potential blood biomarkers for radiation-induced senescence in glioblastoma, the most aggressive…
Meta-analysis of five randomized trials involving 7,246 postoperative colorectal cancer patients demonstrates that anti-inflammatory medications reduce…
Metastatic melanoma cells exhibit elevated levels of lamin B receptor (LBR), a nuclear envelope protein that paradoxically makes their nuclei more fragile…
MYCN, a master regulator oncogene, demonstrates specific transcriptional control mechanisms in hepatocellular carcinoma development, with researchers mapping…
Circulating tumor DNA analysis in blood and urine samples successfully identifies which muscle-invasive bladder cancer patients can avoid radical cystectomy…
A therapeutic compound successfully reactivated mutated p53 protein function in solid tumors, targeting one of the most common genetic alterations in human…
The combination of amivantamab and lazertinib demonstrates therapeutic potential in patients with EGFR-mutated advanced non-small cell lung cancer, targeting…
Rezatapopt demonstrates the ability to restore function to a specific p53 mutation (Y220C) found in roughly 100,000 cancer patients annually. This…
Korean health data from 410,489 smokers tracked over nine years demonstrates that quitting smoking increases Parkinson's disease risk by 60-61% compared to…
Interview research with 51 Turkish-, Moroccan-, and Syrian-Dutch women revealed significant gaps in cervical cancer prevention engagement, with participants…
Fluorescence imaging targeting αvβ3 integrin demonstrated 93% sensitivity and 77% specificity at a cutoff score of 5 for distinguishing benign moles from…
Circulating tumor DNA, cancer cells, and exosomes in blood samples demonstrate enhanced sensitivity over traditional cytology for detecting gallbladder…
VT3989 achieved a 32% overall response rate with 86% disease control in mesothelioma patients when optimal dosing and monitoring protocols were applied…
Taiwanese women born after 1975 in cities and 1980 in rural areas show dramatically elevated cervical cancer risks compared to earlier generations, with urban…