Found 419 results for "longevity"
Scientists at A*STAR have developed a light-controlled hydrogel system that can adjust tissue stiffness in real-time, revealing how mechanical changes in aging…
Advanced mapping techniques reveal that sympathetic nerve density increases in aging ovaries across both human and mouse models, with nerve ablation experiment…
CRISPR-edited human cord blood stem cells carrying the GATA2-R398W mutation display severe mitotic dysfunction and accelerated aging signatures that compromise…
Clinical evidence reveals semaglutide's therapeutic effects extend far beyond its original diabetes indication, with documented benefits across cardiovascular…
Bioengineers have created artificial liver environments using decellularized extracellular matrix scaffolds that successfully induce dormancy in colorectal can…
Adult vaccination appears to fundamentally rewire aging immune systems beyond simple pathogen protection, triggering "trained immunity" that reprograms innate…
Chronic kidney disease represents a significant and underrecognized consequence of SARS-CoV-2 infection, with multiple studies demonstrating elevated CKD risk…
Biogerontology researchers argue that extending human healthspan represents a fundamental ethical obligation rather than merely a beneficial outcome. Their deo…
Analysis of 876,805 Danish women followed for a median 14.3 years revealed that those using menopausal hormone therapy had an 11% reduction in all-cause mortal…
Researchers propose brainspan as a novel metric measuring the duration of life with sufficient neural network efficiency to maintain autonomy, adaptive capacit…
Cognitive resilience, autonomic regulation, sleep architecture, and behavioral capacity emerge as the primary determinants of functional longevity, with progre…
The molecular architecture of life's most abundant macromolecules has remained frustratingly opaque to scientists despite glycans comprising more biological ma…
Cellular energy production may have a more flexible backup system than previously understood, offering new hope for treating metabolic disorders and age-relate…
Chen and colleagues developed OMICmAge, which layers multiple molecular signatures onto DNA methylation patterns to create a more comprehensive biological age…
Understanding how cells absorb nutrients, medications, and other materials from their environment could transform approaches to drug delivery and cellular agin…
Muscle stem cells (MuSCs) undergo a fundamental trade-off with aging, prioritizing their own survival over regenerative capacity through increased expression o…
Two years of caloric restriction in healthy adults produced distinct metabolic signatures across 864 circulating compounds, with three major pathway changes em…
Cross-species research reveals that social isolation and loneliness operate through a destructive feedback cycle, where isolation impairs cognitive control and…
Understanding how blood reaches every neuron in the brain has profound implications for preventing cognitive decline and optimizing brain health throughout agi…
Understanding how cells translate physical forces into survival responses could reshape approaches to age-related tissue deterioration and cancer metastasis. A…