Deleting Lsp2 Gene Extends Drosophila Lifespan Via mTORC1-TOP mRNA Axis
In Drosophila, genetic ablation of Lsp2 — a protein previously classified only as a larval storage protein but now identified as an adipose-tissue effector…
Found 1260 results for "longevity"
In Drosophila, genetic ablation of Lsp2 — a protein previously classified only as a larval storage protein but now identified as an adipose-tissue effector…
A specific probiotic strain, Bifidobacterium pseudocatenulatum CL256B, converts the poorly absorbed citrus flavanone hesperidin into its bioactive form…
A pre-registered systematic review and network meta-analysis of 227 randomised controlled trials compared exercise-only programmes against exercise combined…
Pooling randomized controlled trials comparing ketogenic (KD) and Mediterranean diets (MD) head-to-head in adults, this meta-analysis found KD produced…
Among 2,380 adults who underwent metabolic and bariatric surgery (MBS) between 2008 and 2023, biological age — measured via an AI-derived electrocardiogram…
Understanding how skin detects and responds to dry air has profound implications for conditions ranging from eczema and psoriasis to accelerated skin aging…
Understanding how cells detect nutrient availability and adjust growth accordingly sits at the heart of aging biology, cancer metabolism, and metabolic…
Early cancer detection has long been the most promising — and most elusive — frontier in oncology. The difference between a stage I and stage IV diagnosis can…
A specific dietary amino acid ratio — 0.5% lysine combined with 0.5% arginine — reduces tumor burden and extends survival in tumor-bearing mice, while a…
For the millions of adults over 50 who undergo major elective surgery each year, the choice of anesthetic technique has long carried clinical debate and real…
For decades, pediatric oncology has accepted that high-risk leukemia requires punishing rounds of chemotherapy — with all the neurotoxicity, infection risk…
For anyone tracking longevity interventions, grip strength has long been treated as a reliable proxy for biological age — but a new conceptual analysis…
Strength loss in older adults is rarely attributed to the nervous system, yet the progressive disconnection of motor neurons from muscle fibers may be among…
Understanding why mitochondria deteriorate with age—and whether that deterioration drives aging or merely accompanies it—is one of the central unresolved…
Continuous, unobtrusive monitoring of vulnerable patients has long been a pain point in inpatient care — standard vital-sign checks require physical contact…
Understanding what makes a cell senescent — and distinguishing it from neighboring healthy tissue without chemical labels — has been one of cellular biology's…
Understanding what makes aging cells dysfunctional has long been dominated by genomics — what genes are expressed, silenced, or mutated. But a growing body of…
Tuberculosis remains one of the most consequential infectious disease challenges of our era, and a sweeping new analysis now offers the most granular…
Polysaccharides extracted from Pausinystalia macroceras (PMP) extended lifespan and preserved healthspan in both C. elegans and Drosophila without disrupting…
In a five-group rat model of accelerated brain senescence — combining D-galactose administration with fractionated whole-body γ-radiation (1.5 Gy/week × 4…