CVD Risk Reduction Demands Far More Than 150-Minute Weekly Exercise Threshold
The widely promoted 150-minute-per-week physical activity guideline has long served as a public health benchmark, but a mounting body of evidence suggests it…
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The widely promoted 150-minute-per-week physical activity guideline has long served as a public health benchmark, but a mounting body of evidence suggests it…
The dominant narrative in cardiovascular prevention has long centered on diet, exercise, genetics, and smoking. A sweeping consensus statement from the…
Tuberculosis remains one of the most consequential infectious disease failures of the modern era — a pathogen ancient enough to have infected Egyptian mummies…
Vascular cognitive impairment often goes undetected until significant damage has occurred — partly because clinicians lack agreed-upon diagnostic standards. A…
Among 6,844 English adults aged 50+ tracked across four waves of the English Longitudinal Study of Ageing, greater spirituality, daily prayer/meditation…
Across 12,944 older adults in three nationally representative cohorts — China's CHARLS, England's ELSA, and the US HRS — each one standard-deviation increase…
Decades of vigorous endurance training may confer a physiological paradox: the very habits that protect most people from heart disease appear to create…
Frailty — the syndrome of accumulated physiological decline that predicts hospitalization, disability, and death in older adults — has long resisted early…
Understanding why two people following identical exercise programs achieve vastly different metabolic outcomes has long frustrated clinicians and researchers…
Sleep is increasingly recognized not as passive downtime but as an active physiological process that directly governs the ceiling of human physical…
With Alzheimer's, Parkinson's, and ALS cases climbing globally and no cures in sight, the question of whether lifestyle choices can meaningfully delay or…
Aging-associated gut dysbiosis — marked by depletion of short-chain fatty acid (SCFA)-producing bacteria, accumulation of lipopolysaccharide (LPS) and…
Understanding why some people burn calories more efficiently than others has long frustrated metabolic researchers — and may soon have a more precise…
Across 82,999 US census tracts, nearly 50,000 lack adequate cardiologist access — yet a granular new analysis finds that only 4,765 of the highest-burden…
As semaglutide and tirzepatide reshape obesity medicine, a critical question has emerged that the weight-loss headlines routinely bury: what happens to the…
Across three randomized controlled trials enrolling 171 non-diabetic adults with obesity, GLP-1 receptor agonist therapy produced a mean fat mass reduction of…
Inpatient diabetes management is one of the most consequential yet chronically under-resourced areas of hospital medicine. With roughly one in six UK hospital…
A 12-month pilot randomized controlled trial enrolling 68 adults with prodromal Alzheimer's disease or amnestic mild cognitive impairment found that Partnered…
Pooling three randomized controlled trials — MAVERICK-HCM, ODYSSEY-HCM, and ACACIA-HCM — across 1,156 adults with symptomatic non-obstructive hypertrophic…
Immune checkpoint inhibitors transformed lung cancer treatment, yet most patients who initially respond eventually relapse — and understanding exactly why has…