Found 419 results for "longevity"
Scientists at PNAS have developed a novel bioconjugation technique using activated allylic bromides to selectively modify methionine amino acid residues in pro…
C. elegans nematodes demonstrate sophisticated pathogen avoidance learning through specific neural circuits that transform initial attraction to harmful bacter…
Presbycusis affects two-fifths of adults past 65, yet many dismiss auditory deterioration as inevitable aging rather than seeking intervention. The sensory def…
Researchers developed an artificial intelligence system that predicts where lysine residues undergo post-translational modifications by combining protein langu…
Swiss researchers analyzed circulating proteins in individuals who reached 100+ years, identifying specific molecular markers that distinguish exceptional long…
Rapamycin treatment effectively counteracted liver damage in aging mice fed high-fat diets, suggesting the mTOR pathway inhibitor may protect metabolic organs…
Scientists have identified mitochondrial dysfunction as the critical weakness that allows senolytic drugs to selectively eliminate aged cells. The research rev…
New epigenetic clock research reveals that early-life adversity triggers faster cellular aging in women compared to men, with DNA methylation patterns showing…
The study explores the neural and psychological mechanisms underlying long-term romantic relationships. It suggests that the experience of love and connection…
Stem cells lose their regenerative potency through five interconnected molecular pathways that accelerate with age. Cellular stress accumulation disrupts DNA i…
Troha et al. discovered that kidneys actively filter pro-inflammatory cytokines from circulation and excrete them in urine, functioning as a previously unrecog…
Analysis of UK Biobank participants reveals a precise threshold where vigorous exercise shifts from cognitive protection to harm. Peak brain benefits occur at…
GLOD4 protein actively directs peroxynitrite-mediated nitration to specific cellular targets, contradicting decades of assumptions that this oxidative damage o…
Analysis of Indian demographic data reveals that years of schooling demonstrate a stronger inverse relationship with premature adult mortality than household i…
The MET-PREVENT trial enrolled over 1,000 participants to test whether metformin could delay onset of cardiovascular disease, cancer, dementia, and other age-r…
Cellular organelles actively coordinate to assemble metabolons—structured enzyme complexes that streamline sequential metabolic reactions within pathways. Thes…
Scientists developed molecular aging clocks for ten organs using plasma protein analysis from 43,616 UK Biobank participants, achieving 98% accuracy when teste…
Despite Thailand's international reputation for transgender acceptance and medical expertise, transgender adults face systematic exclusion from the country's h…
The study examines the potential impact of aging populations on the conservation goals of zoos. It suggests that the increasing longevity of animals in captivi…
French researchers have mapped the mechanisms by which mitochondria migrate between adjacent cells, particularly within tumor environments. This intercellular…