Mouse Metabolic Atlas Identifies Alpha-Ketoglutarate as a Candidate Aging Driver
The quest to understand why our bodies deteriorate with age has taken a significant leap forward with the creation of the first comprehensive metabolic map…
Found 1117 results for "longevity"
The quest to understand why our bodies deteriorate with age has taken a significant leap forward with the creation of the first comprehensive metabolic map…
The kidneys' role as guardians of brain health becomes increasingly clear as emerging evidence links declining renal function to accelerated cognitive…
A CRISPR screen revealed that the transcription factor TFAP2C rescues cells from death when the prion-limiting protein hnRNP K is depleted, while connecting…
Senescent cells accumulate within remodeled pulmonary vascular lesions in pulmonary arterial hypertension (PAH), promoting neighboring cell proliferation and…
The persistence of pneumonia and bronchiolitis as humanity's deadliest infectious diseases underscores a critical gap between medical advances and global…
The capacity for developing brains to compensate for early adversity may depend significantly on children's everyday coping abilities, challenging assumptions…
Centenarians achieve exceptional longevity by maintaining immune systems that function remarkably like those of much younger individuals, particularly through…
The world's most comprehensive tracking of respiratory infection deaths reveals a stark contradiction: while medical advances have dramatically reduced death…
Plant survival strategies under oxygen-starved conditions could revolutionize how we approach human cellular stress and longevity interventions. While animals…
The recognition that organ failure can systematically age the immune system represents a paradigm shift in understanding how chronic diseases accelerate…
The timing of cellular stress exposure may hold the key to unlocking longevity benefits, challenging assumptions about stress being universally harmful to…
Nearly half of older adults may harbor silent brain vascular damage that predisposes them to cognitive decline, challenging assumptions about who develops…
The evolution of women's reproductive health technology may hinge on understanding what protection women actually prioritize when given comprehensive options…
The way our bodies handle cellular hydration and mineral transport may need fundamental reconsideration following breakthrough insights into how salts…
The extraordinary longevity of naked mole-rats—living over 30 years with negligible cancer rates—may partly stem from their unconventional approach to body…
The ability to watch molecular processes unfold within individual living cells could revolutionize precision medicine and our understanding of disease…
The ability of cells to recover their reproductive capacity after doubling their entire genetic content may depend on a previously unrecognized chromosomal…
Emergency department intervention with antiviral therapy may represent a critical window for preventing severe COVID-19 outcomes in vulnerable populations…
The pursuit of healthy aging takes on new urgency as evidence mounts that cardiovascular fitness during middle age fundamentally reshapes the trajectory of…
The persistence of lower respiratory infections as humanity's leading infectious killer underscores how prevention strategies still fall short despite…