Found 1260 results for "longevity"
A pilot single-arm trial administered 1 mg/day rapamycin for 4 weeks to 23 cognitively normal adults aged 45–65, stratified by APOE4 genotype. Among the nine…
What if the immune system held the master key to living past 100 in good health? A comprehensive review in Nature Reviews Immunology makes a compelling case…
A whole-food, plant-predominant diet (WFPD) delivers broad cardiometabolic and mental health benefits through multiple converging mechanisms: enhanced…
Among 101 multicellular species capable of living 250 years or longer — 11 animals and 90 plants — a systematic survey of genetic, transcriptomic, proteomic…
Across three cohorts totaling 1,462 adults, a Bayesian ridge regression model applied to resting-state fMRI data produced a Brain Aging Index (BAI) — the…
A dual-compartment metabolic engineering strategy simultaneously activated resveratrol biosynthesis in both the peroxisomes and cytoplasm of Saccharomyces…
Understanding how omega-3 fatty acids exert their well-documented anti-inflammatory and metabolic benefits has long been an incomplete picture. A molecular…
For families living with sickle cell disease or beta-thalassemia, the prospect of a one-time curative intervention has shifted from theoretical to…
Multiple myeloma remains one of the most complex hematologic malignancies to manage, not because effective drugs are lacking, but because the rapidly…
Population-scale health data has long been constrained by cohort sizes too small to detect rare disease patterns or meaningful demographic subgroup…
Growth-related knee pain is quietly undermining youth athletic development, yet the field has lacked good data on which modifiable factors actually drive…
Cholesterol management inside cells is far more intricate than blood lipid numbers suggest, and a new class of molecular tools may redefine how researchers…
How the brain fuels its own activity at the level of individual cells has remained one of neuroscience's most technically intractable questions. A new imaging…
A purified homogalacturonan-type pectin polysaccharide, AAP50-2, isolated from the traditional Chinese herb Anemarrhena asphodeloides, extended maximum…
Every cell in the human body relies on a molecular machine called cytochrome bc1 to convert food into usable energy — and for decades, exactly how this…
Understanding how mitochondrial DNA mutations translate into real cellular dysfunction has been one of the most stubborn technical gaps in aging and metabolic…
GLP-1 receptor agonists have reshaped obesity and diabetes medicine, but a deeper question has lingered: are their wide-ranging benefits incidental side…
The assumption that aging muscles simply need more thyroid hormone to regenerate effectively has guided clinical thinking for decades — and may be…
Personality has long occupied an uneasy middle ground between biology and biography — shaped by genes, upbringing, culture, and chance in ways that were…
Heart failure and cardiac aging have long been linked to declining mitochondrial function, but the precise causal chain — from DNA-level mutations inside…