INDY Gene Reduction Extends Lifespan by Controlling Gut Microbiome Load
Reducing activity of the INDY gene—a citrate transporter—in fruit flies significantly lowers bacterial load while increasing microbiome diversity during aging…
Found 419 results for "longevity"
Reducing activity of the INDY gene—a citrate transporter—in fruit flies significantly lowers bacterial load while increasing microbiome diversity during aging…
The cerebellum's influence on cognitive function represents one of neuroscience's most underappreciated frontiers for healthy aging and brain optimization. Whi…
The discovery of how immune cells precisely orchestrate DNA breaks to create antibody diversity could fundamentally change approaches to immune enhancement and…
Despite three decades of medical progress, respiratory tract infections continue claiming millions of lives annually, highlighting persistent gaps in global he…
The concept that our environment shapes how our brains age has gained powerful new validation through the largest international study to date examining what re…
The extreme physiological demands of space travel may hold unexpected keys to understanding human aging on Earth. Astronauts experience biological changes in m…
A fundamental assumption in cancer biology may need revision: that cellular defects consistently promote or inhibit tumor formation. New findings reveal that d…
The paradox of Asia's respiratory health presents a complex picture for the world's most populous region. While absolute numbers of people living with chronic…
Visual neuroscience has reached a remarkable milestone: the ability to observe individual synapses as they process information from the eye to the brain's visu…
Understanding why some people develop anxiety disorders while others remain resilient may hinge on how quickly the brain's alarm system learns to calm down. Th…
The discovery that specific bacterial toxins create identifiable mutational signatures in human colorectal cancer genomes represents a paradigm shift in unders…
Genetic knockout of the farnesoid X receptor (FXR) dramatically shortened both lifespan and healthspan in male mice, accompanied by accelerated neurodegenerati…
Popular anti-aging supplements could be inadvertently helping one of medicine's most aggressive cancers resist treatment. This discovery challenges the widespr…
Homoharringtonine (HHT), currently FDA-approved for leukemia treatment, selectively eliminates senescent cells in white adipose tissue by binding to heat shock…
Age-related deterioration in sepsis outcomes may stem from fundamental changes in how our gut bacteria interact with intestinal defenses. This mechanistic disc…
Vitamin D supplementation walks a precarious line between therapeutic benefit and serious harm, as demonstrated by a new clinical case that exposes the narrow…
The expanding therapeutic landscape for GLP-1 receptor agonists represents a paradigm shift in treating metabolic dysfunction beyond traditional diabetes manag…
Scientists engineered casein-polyethylene glycol hydrogels using UV-induced crosslinking, achieving 96.31% resveratrol encapsulation efficiency with 86% retent…
AI analysis of handheld ultrasound measurements successfully estimated cardiovascular biological age in 243 adults, correlating strongly with chronological age…
BCLXL-PROTAC, a precision-designed protein degrader, successfully triggered apoptosis in senescent lung cells from COPD patients while sparing healthy cells. T…