Found 419 results for "longevity"
Two previously unknown iridoid glycosides from Verbascum nigrum subspecies abietinum activated multiple stress-resistance pathways in C. elegans worms, upregul…
BCLXL-PROTAC, a precision-designed protein degrader, successfully triggered apoptosis in senescent lung cells from COPD patients while sparing healthy cells. T…
AI analysis of handheld ultrasound measurements successfully estimated cardiovascular biological age in 243 adults, correlating strongly with chronological age…
Terbinafine, a widely-used antifungal medication, and miglustat, a rare disease treatment, both extended lifespan in C. elegans by activating mitochondrial str…
Researchers using 5×FAD Alzheimer's mice discovered that dying brain cells release spermidine, a metabolite that triggers autophagy—the cellular cleanup proces…
Analysis of 25 rodent longevity models reveals that enhanced blood flow and angiogenesis drive healthful aging in only seven cases, with brown adipose tissue (…
The vast majority of human genetic variants linked to disease risk lie outside protein-coding regions, creating a massive blind spot in precision medicine. Whi…
N-acetylneuraminic acid (Neu5Ac), a sialic acid found in bird's nest and human milk, demonstrated remarkable gut-protective effects in both aging and inflammat…
The quest to measure how fast we truly age has moved far beyond counting birthdays. While chronological age ticks uniformly forward, biological age varies dram…
The long-suspected connection between psychological stress and hair loss now has a clear molecular pathway. Understanding how stress translates into visible he…
Understanding how the human brain builds itself could unlock new approaches to treating neurological diseases and potentially extending cognitive healthspan. T…
The vast universe of potentially functional proteins remains largely unexplored due to evolutionary bottlenecks that may constrain therapeutic innovation. Whil…
Understanding how skin naturally sheds dead cells could revolutionize approaches to treating aging, acne, and barrier dysfunction disorders that affect million…
The cardiovascular field may be witnessing a paradigm shift in how we approach the body's most critical blood pressure pathway. Rather than continuing to focus…
The discovery that specific long non-coding RNAs orchestrate cellular aging could fundamentally alter how we approach age-related disease prevention. These reg…
The ability to reach 100 years while maintaining relatively good health represents one of biology's most intriguing phenomena, yet the metabolic signatures tha…
Regular nut consumption emerges as one of the most consistently validated dietary interventions for extending healthy lifespan, with mounting evidence showing…
The golden hours following a heart attack may determine not just immediate survival, but life expectancy years into the future. This reality takes on new urgen…
The central mystery of human vision—why our sharpest sight depends on a tiny retinal region packed exclusively with red and green light sensors—has been decode…
IGF-1 signaling operates through a previously unrecognized temporal switch that determines whether cells repair or senesce. Acute IGF-1 exposure promotes tissu…