Found 1260 results for "longevity"
The class of drugs that reshaped obesity and metabolic medicine may be on the verge of a more profound repositioning — as genuine longevity agents. If GLP-1…
Short-course sodium valproate — an anticonvulsant repurposed as a cardioprotective agent — administered at 15 mg/kg/day for ≤14 days before cardiac surgery…
A data-driven screen of 16 extract combinations derived from broccoli, licorice, passionflower, and lemon balm identified an optimized three-component blend…
Understanding how infectious disease patterns shift under major societal disruptions reveals something important about transmission dynamics that routine…
The timing of food intake is emerging as a variable nearly as consequential as what or how much is eaten — a shift that reframes decades of nutrition research…
Brown adipose tissue is one of the body's most potent metabolic engines — capable of burning calories to generate heat rather than storing them. Any signal…
Among 5,844 postmenopausal women tracked from the mid-1990s, every standard deviation increase in epigenetic age acceleration (EAA) reduced odds of surviving…
Heat stress in Siberian sturgeon triggers UCP1-mediated uncoupling of ATP synthesis from oxidative phosphorylation, starving intestinal villi of energy and…
Accurately measuring pain in children—especially in infants and neonates who cannot self-report—remains one of pediatric medicine's most persistent clinical…
For the millions of adults experimenting with low-carbohydrate eating patterns, a critical question has remained unanswered: does it matter whether…
Tuberculosis remains one of the most consequential but underappreciated threats to global longevity, and this sweeping analysis arrives at a moment when…
A conceptual shift in how we classify disease burden may fundamentally alter where global health investment flows — and how much return humanity can expect…
Tick-borne illness rarely dominates longevity conversations, yet Lyme disease now infects an estimated 476,000 Americans annually — a burden that has quietly…
Chronic low-grade inflammation — now widely recognized as a central driver of aging — has long resisted targeted intervention because its origins are diffuse…
The single greatest determinant of whether a health system can deliver on its promises is whether trained workers are actually there to do the work. A…
ABL1 tyrosine kinase directly binds mTOR and, in aged mice modeling postoperative cognitive dysfunction (POCD), drives excessive microglial autophagy and…
FGF21 (fibroblast growth factor 21) reverses senescence in aged human adipose-derived mesenchymal stem cells (ASCs) by restoring impaired autophagy flux…
As digital tools reshape orthopedic surgery, understanding which technologies are ready for the operating room versus which remain experimental matters…
Most dementia risk scores focus on lifestyle factors and genetics measured close to diagnosis — but a growing body of evidence suggests the biological seeds…
The ability to measure whether an anti-aging intervention is actually working — without waiting decades for mortality outcomes — has been one of the central…