ARDD 2025: Aging Field Pivots From Description to Engineered Longevity Interventions
For decades, aging research catalogued what goes wrong in aging bodies. The 2025 Aging Research and Drug Discovery conference signals a pivotal maturation…
Found 1260 results for "longevity"
For decades, aging research catalogued what goes wrong in aging bodies. The 2025 Aging Research and Drug Discovery conference signals a pivotal maturation…
For the hundreds of millions living with psychosis worldwide, the gap between international human rights standards and daily reality remains vast — and…
Spatial proteomics applied to murine colonic mucosa reveals a coordinated cluster of age-associated molecular disruptions: senescent T cells physically…
Pooling 54 prospective and retrospective cohort studies encompassing 1,833,267 participants and 346,034 deaths, this meta-analysis quantifies Mediterranean…
In a randomized, double-blind, placebo-controlled substudy of the PROBIOSENIOR trial, 46 adults aged 60+ received either SYNBIO® probiotics at 5×10⁹ CFU daily…
At 20 mg/kg co-administered with dexamethasone (7 mg/kg IM weekly for 5 weeks) in a rat model, spermidine reversed key markers of glucocorticoid-induced…
Cardiac NAD+ depletion creates a cascade of mitochondrial dysfunction, elevated reactive oxygen species, and cardiomyocyte death — with the rate-limiting…
Ovarian aging accelerates through cellular senescence cascades: primordial follicle depletion, SASP-driven stromal inflammation, mitochondrial dysfunction…
A pilot study of 80 healthy Chinese participants across four age cohorts (centered at 10, 30, 50, and 70 years) mapped bacterial and fungal communities on…
Every decade or so, a technological shift compresses pharmaceutical timelines that once spanned fifteen years into something far shorter. The emergence of…
Copper is one of biology's most paradoxical minerals — essential in trace amounts yet lethal when it accumulates in the wrong cellular compartment. A…
How Americans actually die is more complex than official death statistics suggest — and that gap between recorded data and biological reality has major…
Most people assume a more reactive immune system is unconditionally protective — this research challenges that intuition in a clinically precise way, with…
Screening 991 blood metabolites against cognitive performance and brain MRI markers in 1,082 dementia-free middle-aged participants (Rotterdam Study), this…
Understanding how oxygen levels regulate immune responses could reshape how scientists approach inflammatory diseases and hypoxia-related conditions in humans…
Understanding what actually executes p53's tumor-suppressing and aging-related commands inside living organisms—not just in cell cultures—has been one of…
For a population carrying a disproportionate Alzheimer's burden, identifying early, measurable warning signs before cognitive decline appears is one of…
For the millions of adults managing atrial fibrillation, deep vein thrombosis, or cardiovascular risk, the promise of stopping dangerous clots without…
Among 872 hospitalized adults aged ≥65 in Italy's Report-AGE cohort, shorter-than-expected leukocyte telomere length — expressed as age-adjusted residuals…
A bibliometric analysis of 858 telomere-exercise publications from 2000–2025 documents a field-wide mechanistic pivot: the research landscape shifted from…